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Vitamin D3 600 IU
Vitamin D3 600 IU

Vitamin D3 600 IU


   Vitamin D3 (cholecalciferol) 600 IU it is recommended as a dietary supplement — an additional source of vitamin D.


   Vitamin D3 is a fat-soluble substance that has a multifaceted effect on the body. Vitamin D3 is essential in processes:
  • formation of bone tissue cells osteoblasts;
  • immune cells work;
  • conduction of excitation pulses through nerve and muscle fibers;
  • functioning of skeletal muscle, heart muscle;
  • metabolism in skin cells.

   The most important function of vitamin D3 is to control calcium metabolism. Vitamin D3 provides a balance of calcium and phosphorus in the blood. It is vital because a change in the concentration of calcium in the blood even by 1% causes severe disorders in the body:

  • the excitability of nerve endings changes;
  • muscle conduction is impaired;
  • the penetration of minerals into cells worsens;
  • the activity of many enzymes decreases;
  • disturbed hormonal regulation of metabolism.

   Lack of vitamin D3 in younger age causes in older children incorrect posture and curvature of the spine. It becomes the cause of joint mobility disorders in 30-year-olds and the development of arthritis in adults.

   Also, Vitamin D3:
  • participates in the processes of cell growth, division, and differentiation;
  • there is evidence that vitamin D controls the production of cholesterol and prevents the for-mation of cholesterol plaques in the blood vessels, preventing atherosclerosis;
  • considered an essential factor in the prevention of malignancies;

1 capsule contains: Vitamin D3 — 15 mcg (600 IU).

Component
Content in 1 capsule, mcg Recommended daily con-sumption level (RDCL), mcg % of RDCL*
Vitamin D3 15 ± 1,5 5 300**

* TR CU 022/2011 "Food products in terms of its labeling";
** Does not exceed the acceptable upper consumption level.

Dietary supplement «Vitamin D3 (cholecalciferol) 600 IU» is registered by the Federal service for supervision of consumer protection and human welfare. Certificate of State Registration No. RU.77.99.88.003.R.003631.10.19 dated 03.10.2019, Technical Specifications (TS) 10.89.19-044-78056148-2019.

Composition: refined vegetable oil, vitamin D3, capsule shell (gelatin, glycerin (water-retaining agent), water, sodium benzoate (preservative), ethyl vanillin (flavor)).

Release form: oval soft gelatin capsules weighing 410 mg, 60 capsules in consumer packaging.

Recommended use: Adults 1 capsule daily with a meal. The period of administration is 2-3 months. It is recommended consulting a doctor before administration. It is not a medicine.

Contraindications: Hypersensitivity of the components.

Vitamin D3 2000 IU
Vitamin D3 2000 IU

Vitamin D3 2000 IU


   Vitamin D3 (cholecalciferol) 2000 IU it is recommended as a dietary supplement — an additional source of vitamin D.


   Vitamin D3 is a fat-soluble substance that has a multifaceted effect on the body. Vitamin D3 is essential in processes:
  • formation of bone tissue cells osteoblasts;
  • immune cells work;
  • conduction of excitation pulses through nerve and muscle fibers;
  • functioning of skeletal muscle, heart muscle;
  • metabolism in skin cells.

   The most important function of vitamin D3 is to control calcium metabolism. Vitamin D3 provides a balance of calcium and phosphorus in the blood. It is vital because a change in the concentration of calcium in the blood even by 1% causes severe disorders in the body:

  • the excitability of nerve endings changes;
  • muscle conduction is impaired;
  • the penetration of minerals into cells worsens;
  • the activity of many enzymes decreases;
  • disturbed hormonal regulation of metabolism.

   Lack of vitamin D3 in younger age causes in older children incorrect posture and curvature of the spine. It becomes the cause of joint mobility disorders in 30-year-olds and the development of arthritis in adults.

   Also, Vitamin D3:
  • participates in the processes of cell growth, division, and differentiation;
  • there is evidence that vitamin D controls the production of cholesterol and prevents the for-mation of cholesterol plaques in the blood vessels, preventing atherosclerosis;
  • considered an essential factor in the prevention of malignancies;

1 capsule contains: Vitamin D3 — 15 mcg (600 IU).

Component
Content in 1 capsule, mcg Recommended daily con-sumption level (RDCL), mcg % of RDCL*
Vitamin D3 50 5 1,000**

* TR CU 022/2011 "Food products in terms of its labeling";
** Does not exceed the acceptable upper consumption level.

Certificate of State Registration № AM.01.06.01.003.R.000006.01.20 dated 15.01.2020, Tech-nical Specifications (TS) 10.89.19-047-78056148-2019

Composition: vegetable oil (sunflower), cholecalciferol (2,000 IU vitamin D3), capsule shell (gelatin, glycerin (water-retaining agent), water, sodium benzoate (preservative), ethyl vanillin (flavor)).

Release form: oval soft gelatin capsules weighing 570 mg, 30 capsules in consumer packaging.

Recommended use: Adults 1 capsule daily with a meal or as recommended by a healthcare practitioner. The period of administration is one month. It is recommended to consult a doctor before administration. It is not a medicine.

Contraindications: Hypersensitivity of the components, hypervitaminosis D3, pregnancy, and lactation.

Vitamin D3 for children
Витамин D3 для детей

Vitamin D3 for children


      Vitamin D is the common name for a group of fat-soluble vitamins that have a multifaceted effect on the human body. One of the most important functions of vitamin D is to control the balance of calcium and phos-phorus in the blood. A 1% change in balance causes a serious disruption of the entire body. Two forms of vitamin D with similar characteristics are the most important: D3 (cholecalciferol) and D2 (ergocal-ciferol).

   Vitamin D is actively involved in processes:
  • the formation of osteoblast bone tissue cells;
  • functioning of the skeletal musculature;
  • conduct of excitation impulses through nerve and muscle fibers;
  • cardiac muscle activity;
  • metabolic processes in skin cells;
  • immune system functioning [1].

Vitamin D deficiency results in bone deformities (rickets) and increases the risk of fractures. Children with vitamin D deficiency tend to be more irritable, have poorer development (begin to walk later), and have a poor appetite. These manifestations are accompanied by delayed teething and dental enamel pathology [2].

According to many clinical studies, chronic vitamin D deficiency in young children is associated with a high risk of future development of various diseases: diabetes mellitus, obesity, autoimmune diseases, cancer, cardiovascular diseases, psoriasis, atopic diseases, inflammatory bowel diseases [3].

Sources of vitamin D

Vitamin D is formed in the skin by sunlight. Also, vitamin D is present in food: fatty fish (mackerel, salmon, sardine, tuna - 250 - 300 IU/100 g), egg yolk (20 IU in one chicken yolk), mushrooms (100 IU/100 g of fresh mushrooms) [4]. The formation of vitamin D in the skin under the influence of sunlight is influenced by geographic latitude, time of year, time of day, cloud cover, and degree of air pollution [5]. Given the geographical location of Russia, vitamin D is produced in sufficient quantities in the skin only on summer sunny days. A child should be exposed to direct sunlight for at least 30 minutes a week without clothes on, or 2 hours a week if only the face and limbs are covered [4]. People with dark skin have lower vitamin D production capacity, as melanin serves as a barrier to sunlight. Sunscreen with an SPF of 8 or higher reduces vitamin D production in the skin by 95% [6].

With food, a child receives on average 150 to 250 IU of vitamin D per day. The growing body's need for vitamin D is 5 to 10 times higher, and this is especially true for children of early childhood and adolescence [2].

Under the national program for the correction of vitamin D deficiency in children in the Russian Federation, adopted in 2018 the Union of Pediatricians of Russia recommends that children of all ages take preventive doses of vitamin D [7].

The recommended daily intake of dietary supplement (1 capsule) content.

Component

Content in the recommended daily dose, mcg

Satisfying the physiological needs of the body, %

Children from 3 to 7 years old*

Children from 7 to 11 years old*

Children 11 to 14 years old*

Children from 14 to 18 years old*

Adults**

Boys

Girls

Young men

Girls

Vitamin D3

9,8 - 10

98 - 100

98 - 100

98 - 100

98 - 100

98 - 100

98 - 100

196 - 200***

* - according to methodical recommendations 2.3.1.2432-08 "Norms of physiological requirements for energy and nutrients for various groups of population of the Russian Federation";
** - according to the TR CU 022/2011 "Food products in terms of its labeling" (Annex 2);
*** - does not exceed the upper permissible level of consumption, according to "Unified sanitary-epidemiological and hygienic requirements for goods subject to sanitary-epidemiological supervision (control)" (Appendix 5).

Certificate of state registration № RU.77.99.11.003.R.003713.11.20 dated 10.11.2020, Technical Specifications (TS) 10.89.19-051-78056148-2020.

Release form: round seamless soft gelatin capsules weighing 200 mg, 3 blisters of 10 capsules in a consumer packaging.

Composition: unrefined vegetable oil or a mixture of refined and unrefined oils (sunflower, or soybean, or olive), capsule shell (gelatin, glycerin (water-retaining agent), water, citric acid (acidity regulator)), vitamin D3 (cholecalciferol), dl-alpha-tocopherol (antioxidant). The company produces products containing fish oil, lactose, soy lecithin

1 capsule contains: vitamin D3 (cholecalciferol) — 10 micrograms (400 IU).

Scope: Recommended as a dietary food supplement - an additional source of vitamin D3..

Recommended use: Adults and children over 3 years: 1 capsule 1 time a day with meals. The duration of intake is 1 month. Before using it is recommended to consult a doctor. Before using dietary supplements for children should consult a pediatrician.

Contraindications: Hypersensitivity to the components, pregnancy, and lactation.

Shelf life: 2 years.

Storage conditions: keep in a dry place, out of a child’s reach at a temperature of no more than 25°C.

______________________________________________________________________________________________________________

[1]. Malcev S.V.,Rylova N.V. Vitamin D and immunity. Edition | 2015, Pediatrics, PM

[2] http://www.odb.tambov.gov.ru/index.php/kontakty/stranichka-pediatra/profilaktika-defitsita-vitamina-...

[3]. Vitamin D insufficiency in children and adolescents of the Russian Federation : modern approaches to correction : a national program / FGBUN "FITs Nutrition and Biotechnology", FGBOU NRDC of the Ministry of Health of Russia, FGBOU DPO RMAPO of the Ministry of Health of Russia; under the patronage of the Union of Pediatricians of Russia. - Moscow : Pediatr, 2018. - — 9 с.

[4]. ]. Prevention and treatment of vitamin D deficiency: a modern view of the problem. Y.S. Lashkova. Scientific Center for Children's Health, Moscow, Russian Federation//Pediatric Pharmacology /2015/ vol. 12/ no. 1/.

[5]. Wacker M., Holick M. F. Vitamin D — effects on skeletal and extraskeletal health and the need for supplementation. Nutrients. 2013 Jan 10; 5 (1): 111–48

[6] Iyer P., Diamond F. Detecting disorders of vitamin D deficiency in children: an update. Adv Pediatr. 2013; 60 (1): 89–106. 5. Holick M. F. Vitamin D deficiency. N Engl J Med. 2007; 357: 266–281.

[7]. https://www.pediatr-russia.ru/parents_information/soveti-roditelyam/vitamin-d.php

Vitamins A+E
Витамины А+Е

Vitamins A+E

    It is recommended as a dietary supplement — an additional source of vitamins А and Е.

    Action of preparation is determined by the properties of its fat-soluble vitamins A and E.

    Retinyl palmitate (vitamin А) is a fat-soluble vitamin playing an essential role in oxidative-recovery processes, participates in the synthesis of complex carbohydrates, proteins, and fats. It is required for normal reproductive function, fetal development, restoration of skin and mucous membrane cells, and formation of bone tissue. It participates in vision mechanism. Retinyl increases the immunity, alleviates consequences of some infectious diseases, and may prevent the development of a malignant neoplasm.

    Alpha-tocopherol acetate (vitamin E) prevents the destruction of cell membranes, participates in protein synthesis, cell division processes, cellular respiration, favorably influences on disturbed lipid metabolism. Vitamin Е maintains the stability of red corpuscles and prevents their decomposition, prevents increased permeability and capillary fragility, increases cellular resistance to an oxygen deficit. Vitamin Е also promotes recovery of skeleton muscles at muscular dystrophy and other muscle injuries. At cardiovascular diseases in complex therapy, vitamin E promotes regulation of metabolism in heart muscle, increases the blood velocity and maintains potential in tiny vessels. Vitamin Е also promotes regulation of the function of sex glands in men.

One capsule contains: alpha-tocopherol acetate — 100 mg (100 IU), retinyl palmitate — 4.7 mg (8,000 IU).

A daily serving contains:

Component
Content in 1 capsule, mg Recommended daily consumption level (RDCL) % of RDCL
Vitamin А
2,4±0,24
0,8 mg
300*
Vitamin Е
65,0±6,5
10 mg 650*

** Does not exceed the acceptable upper level of consumption.

«Vitamins A+E» has the registration of the Russian Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing (Rospotrebnadzor). Certificate of State Registration No. RU.77.99.88.003.Е.004126.09.18 dated 19.09.2018. Technical Specifications (TS) 10.89.19-033-78056148-2016.

Composition: vegetable unrefined or a mixture of a refined and unrefined oils (sunflower, or soya or, olive), alpha-tocopherol acetate, retinol palmitate, capsule shell (gelatin, glycerin (water-retaining agent), water, sodium benzoate (preservative), ethylvanillin (flavor)*).
*- for oval capsules

Recommended use: Adults 1 capsule one time daily with meals. The period of administration — 2-4 weeks. If required, the administration can be repeated in a month. It is recommended consulting a doctor before administration. It is not a medicine.

Contraindications: Hypersensitivity of the components, pregnancy, and lactation.

Vitamin E
Vitamin E

Vitamin E

Vitamin E

    It is recommended as a dietary supplement – an additional source of vitamin E.

    Vitamin Е is a universal antioxidant slowing down free-radical reactions, prevents the formation of toxins damaging cell membranes, protects from the oxidation of vitamin A, improves cellular respiration, promotes the economy of oxygen consumption by cells. Vitamin Е controls the biosynthesis of coenzyme Q (Ко Q10) — indispensable component in the cellular power production chain.

    Vitamin Е participates in cell division and cellular metabolism processes, prevents increased permeability and capillary fragility.

    Vitamin Е stimulates protein synthesis (collagen, enzymic, structural and contractile proteins of a skeleton and smooth muscles, myocardium), regulates cholesterol synthesis.

    The deficit of Vitamin E results in the partial destruction of red corpuscles, reduction of activity of antioxidative protection enzymes in them. Increase of membrane permeability of all cells and subcellular structures, accumulation of toxins (products of lipid peroxidation). These are the particular reason for various symptoms of the deficit of vitamin E – from muscular dystrophy and infertility to hepatic necrosis and colliquation of brain regions, especially tentorium.

    The deficit of vitamin E in humans could be due to nutritional habits (for instance, the absence of vegetable oils in food) or due to various diseases such as hepatic, pancreas gland disease.

Content of alpha-tocopherol acetate (mg/IU) in 1 capsule: 100 mg (100 IU) in capsule of 250 mg; 200mg (200IU) in capsule of 400 mg.

Daily serving contains:

Component
Form of presentment
Content in 1 capsule, mg Recommended daily consumption level (RDCL) % of RDCL
Vitamin Е
400 mg capsules
130 10 mg
1300**
Vitamin Е
250 mg capsules
65 10 mg 650**

* does not exceed the acceptable upper consumption level.

«Vitamin E» has the registration of the Russian Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing (Rospotrebnadzor). Certificate of State Registration No. RU.77.99.88.003.Е.004812.11.17 dated 13.11.2017, Technical Specifications (TS) 10.89.19-032-78056148-2016.

Composition: vegetable, unrefined or mixture of refined and unrefined oil: (sunflower or soya or olive) oil, alpha-tocopherol acetate, capsule shell (gelatin, glycerin (water-retaining agent), water, sodium benzoate (preservative), ethyl vanillin (flavor)*.
*for oval capsules

Recommended use: Adults 1 capsule one time daily with meals. The period of administration — 2-4 weeks. If required, the administration may be repeated in a month. It is recommended consulting a doctor before administration. It is not a medicine.

Contraindications: Hypersensitivity of the components, pregnancy, and lactation.